Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes, fungi, and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. Neryl diphosphate is a precursor for monoterpenes such as mycrene and cyclic monoterpenes such as limonene.
Provided as the tris-ammonium salt
Featured in Publications
1. Nagel, R., J. Gershenzon, et al. (2012). “Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry.” Analytical Biochemistry 422(1): 33.
2. Falara, V., Akhtar, T. A., Nguyen, T. T. H., Spyropoulou, E. A., Bleeker, P. M., Schauvinhold, I., … Pichersky, E.(2011). “The tomato terpene synthase gene family.” Plant Physiology, 157(2), 770-789. DOI:10.1104/pp.111.179648
3. Demissie, Z., et al. (2012). “Cloning, functional characterization and genomic organization of 1,8-cineole synthases from Lavandula.” Plant Mol Biol 79(4): 393.
4. Johnson, S. R., et al. (2019). “Promiscuous terpene synthases from Prunella vulgaris highlight the importance of substrate and compartment switching in terpene synthase evolution.” New Phytologist 223(1): 323-335.
Alternate Names: Neryl pyrophosphate, NPP
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