Isopentenyl Diphosphate (IPP)

Product Number: I-0050

Isopentenyl Diphosphate (IPP) - Echelon Biosciences

Support

Isopentenyl diphosphate (IPP) is a building block in the isoprenoid biosynthesis pathway. Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes, fungi, and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway.

Provided as the tris-ammonium salt

Alternate Names: Isopentenyl pyrophosphate, IPP

Bulk discounts available, please email echelon@echelon-inc.com for information.

Categories	Biochemical Reagents
Filter	Isoprenoid, Isoprenoid Diphosphate
CAS Number	116057-53-5
Molecular Formula	C5H21N3O7P2
Molecular Weight (g/mol)	297.18
Purity	>95%
Storage	-20 °C or below

Technical Data Sheet

1. Wouters, J., Y. Oudjama, et al. (2003). “Structure and mechanism of action of isopentenylpyrophosphate- dimethylallylpyrophosphate isomerase.” J Am Chem Soc 125(11): 3198-9.
2. Schilmiller, A. L., I. Schauvinhold, et al. (2009). “Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate.” Proceedings of the National Academy of Sciences 106(26): 10865-10870.
3. Bang, S., S. Yoo, et al. (2010). “Farnesyl pyrophosphate is a novel pain-producing molecule via specific activation of TRPV3.” J Biol Chem 285(25): 19362-71.
4. Haymond, A., et al. (2014). “Kinetic Characterization and Allosteric Inhibition of the Yersinia pestis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (MEP Synthase).” PLoS ONE 9(8): e106243.
5. Wang, X., et al. (2018). “MEPicides: α,β-Unsaturated Fosmidomycin Analogs as DXR inhibitors against Malaria.” J Med Chem 61(19): 8847-8858.
6. Rea, K. A., et al. (2019). “Biosynthesis of cannflavins A and B from Cannabis sativa L.” Phytochemistry 164: 162-171.

You may also like…

Biochemical Reagents
Farnesyl Diphosphate (FPP)

Product Number: I-0150

$203 – $722 View products
Biochemical Reagents
Neryl Diphosphate (NPP)

Product Number: I-0120

$219 – $725 View products
Biochemical Reagents
Geranyl Diphosphate (GPP)

Product Number: I-0100

$209 – $596 View products
Biochemical Reagents
Dimethylallyl Diphosphate (DMAPP)

Product Number: I-0051

$137 – $521 View products