2Z,6Z-Farnesyl Diphosphate

Product Number: I-0170

$264.00$2,018.00

$264.00
$2,018.00

Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes, fungi, and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. 2Z,6Z-Farnesyl diphosphate is synthesized by Z-farnesyl diphosphate synthase (M. tuberculosis) from neryl diphosphate.  It is not a substrate for protein-farnesyl transferase.

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Categories

Biochemical Reagents

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Isoprenoid, Isoprenoid Diphosphate

CAS Number

27248-37-9

Molecular Formula

C15H37N3O7P2

Molecular Weight (g/mol)

433.4

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

1) Bleeker, P., E. Spyropoulou, et al. (2011). “RNA-seq discovery, functional characterization, and comparison of sesquiterpene synthases from Solanum lycopersicum and Solanum habrochaites trichomes.” Plant Molecular Biology 77(4-5): 323-336.
2) Nagel, R., J. Gershenzon, et al. (2012). “Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry.” Analytical Biochemistry 422(1): 33.
3) Falara, V., Akhtar, T. A., Nguyen, T. T. H., Spyropoulou, E. A., Bleeker, P. M., Schauvinhold, I., … Pichersky, E. (2011). “The tomato terpene synthase gene family.” Plant Physiology, 157(2), 770-789. DOI:10.1104/pp.111.179648

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