CYM50308 (S1P4 Receptor Agonist)

Catalog No.:  B-0060
MW: 405.46
Purity: >98%
CAS: 1345858-76-5

Description:  CYM50308 is a potent and selective S1P4 receptor agonist with EC50 of 37.7 nM - 79.1nM. It is inactive against the S1P1, S1P2, and S1P3 receptors up to 25 μM, and the S1P5 receptor up to 2.1 μM.


4 °C


1) Urbano et al. Discovery, synthesis and SAR analysis of novel selective small molecule S1P4-R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2- (alkylimino)thiazolidin-4-one chemotype, Bioorganic & Medicinal Chemistry Letters, 2011, 6739-6745.
2) Guerrero et al. Identification of a novel agonist of the sphingosine 1-phosphate receptor 4 (S1P4), Probe Reports from the NIH Molecular Libraries Program.

Related Products

Sphingosine Kinase Inhibitor (SK1-II) B-0024)
2-Acetyl-5-tetrahydroxybutyl imidazole (THI) (B-0031)
NVP-231 (Ceramide kinase Inhibitor)(B-0040)
FTY-720 (B-0720)
(S)-FTY720 Phosphate (B-0721)

Options/Sizes Pricing
B-0060-10mg $ 189.00
B-0060-25mg $ 454.00
B-0060-50mg $ 889.00
Additional Information:
Tech Data Sheet - B-0060

Add a specific quantity to your cart    *  

Back to the webstore startpage      Back to the product overview      Your Shopping Cart      Terms of Service

assay and reagents for drug discovery in lipid signaling pathways