TT3, together with helper lipid, DMG-PEG2000, Cholesterol, and mRNA formed TT3 lipid nanoparticles (LNPs) which improve the delivery efficiency of firefly luciferase FLuc mRNA over 350-fold in vitro. TT3 LNPs with human factor IX (hFIX) mRNA can efficiently improve the hFIX level to normal physiological values in FIX-knockout mice.
| Categories | Lipids |
|---|---|
| Filter | Ionizable/Cationic Lipids |
| CAS Number | 1821214-50-9 |
| Molecular Formula | C90H174N6O3 |
| Purity | >95% |
| Storage | -20 °C or below |
| Shipping Temp | Room Temperature |
