Product Number: N-1020
ALC-0315 is an ionizable lipid which has been used to form lipid nanoparticles for delivery of RNA. [Read More...]
ALC-0315 is an ionizable lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0315 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0159, DSPC, and cholesterol. This is a reagent grade product, for research use only.
| CAS Number | 2036272-55-4 |
|---|---|
| Molecular Formula | C48H95NO5 |
| Molecular Weight (g/mol) | 766.29 |
| Purity | >95% |
| Categories | Lipids |
| Filter | Ionizable/Cationic Lipids |
| Storage | 4 °C or below |
| Shipping Temp | Gel Ice |
1) Hirota, M., et al. (2023). “Human immune and gut microbial parameters associated with inter-individual variations in COVID-19 mRNA vaccine-induced immunity.” Communications Biology 6(1): 368.
2) R. Tenchov, R. Bird, A. E. Curtze, Q. Zhou (2021) “Lipid Nanoparticles—From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement” ACS Nano, DOI: 10.1021/acsnano.1c04996.
3) K.H. Moss, P. Popova, et al. (2019) “Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides” Mol. Pharmaceutics 16, 2265–2277, DOI: 10.1021/acs.molpharmaceut.8b01290.
4) Y. Duan, A. Dhar, et al. (2020) “A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems” RSC Adv.,10, 26777-26791.
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