ALC-0315

Product Number: N-1020

$75.00$390.00

$75.00
$125.00
$390.00
SKU: N-1020 Category: Tag:

ALC-0315 is an ionizable lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0315 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0159, DSPC, and cholesterol. This product is for research use only and not for human use.

References

1) R. Tenchov, R. Bird, A. E. Curtze, Q. Zhou (2021) “Lipid Nanoparticles—From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement” ACS Nano, DOI: 10.1021/acsnano.1c04996.
2) K.H. Moss, P. Popova, et al. (2019) “Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides” Mol. Pharmaceutics 16, 2265–2277, DOI: 10.1021/acs.molpharmaceut.8b01290.
3) Y. Duan, A. Dhar, et al. (2020) “A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems” RSC Adv.,10, 26777-26791.

CAS Number

2036272-55-4

Molecular Formula

C48H95NO5

Molecular Weight (g/mol)

766.29

Purity

>95%

Storage

-20 °C or below

Categories

Lipids

Filter

Cationic Lipids

Technical Data Sheet

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