BODIPY FL PI(4)P

Product Number: C-04F6

$344.00$602.00

$344.00
$602.00
SKU: C-04F6- Category: Tags: , , , , ,

BODIPY FL PI(4)P (BODIPY FL Phosphatidylinositol 4-phosphate) is a water soluble analog of PI(4)P labeled with the green fluorophore, Bodipy®-FL at the sn-1 position.


Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4,5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.

Excitation/Emission

503/513 nm

Storage

-20 °C, protect from light

Featured in Publications

1) Caromile, L. A., A. Oganesian, et al. (2010). “The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.” J Biol Chem 285(14): 10487-96.
2)Rudge, S. A., D. M. Anderson, et al. (2004). “Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.” Mol Biol Cell 15(1): 24-36.
3) Oganesian, A., M. Poot, et al. (2003). “Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation.” Proc Natl Acad Sci U S A 100(13): 7563-8.

Bulk discounts available, please email echelon@echelon-inc.com for information.


Categories

Lipids

Filter

Fluorescent, Phosphoinositides, PI(4)P

Excitation/Emission

503/513 nm

Molecular Formula

C55H103BF2N6O17P2

Molecular Weight (g/mol)

1,231.19

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

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