BODIPY FL PI(4)P

Product Number: C-04F6

$379
$664

BODIPY FL PI(4)P (BODIPY FL Phosphatidylinositol 4-phosphate) is a water soluble analog of PI(4)P labeled with the green fluorophore, Bodipy®-FL at the sn-1 position.


Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4,5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex.

Bulk discounts available, please email echelon@echelon-inc.com for information.

Categories

Lipids

Filter

Fluorescent, Phosphoinositides, PI(4)P

Excitation/Emission

503/513 nm

Molecular Formula

C55H103BF2N6O17P2

Molecular Weight (g/mol)

1,231.19

Purity

>95%

Storage

-20 °C or below

Shipping Temp

Dry ice or gel ice depending on destination

Technical Data Sheet

1) Caromile, L. A., A. Oganesian, et al. (2010). “The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion.” J Biol Chem 285(14): 10487-96.
2)Rudge, S. A., D. M. Anderson, et al. (2004). “Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.” Mol Biol Cell 15(1): 24-36.
3) Oganesian, A., M. Poot, et al. (2003). “Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation.” Proc Natl Acad Sci U S A 100(13): 7563-8.

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