BODIPY TMR PI(3)P

Product Number: C-03M6

$542
$934

BODIPY TMR PI(3)P (BODIPY TMR Phosphatidylinositol 3-phosphate) is a water soluble analog of PI(3)P labeled with the orange fluorophore, Bodipy®-TMR, at the sn-1 position.


Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate (PI(3)P) is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.

Bulk discounts available, please email echelon@echelon-inc.com for information.


Categories

Lipids

Filter

Fluorescent, Phosphoinositides, PI(3)P

Excitation/Emission

542/574 nm

Molecular Formula

C33H50N5Na3O20P2

Molecular Weight (g/mol)

1422.42

Purity

>95%

Storage

-20 °C or below, protect from light

Shipping Temp

Dry ice or gel ice depending on destination

Technical Data Sheet

1) Stankewicz, C. and F. H. Rininsland (2006). ” A robust screen for inhibitors and enhancers of phosphoinositide-3 kinase (PI3K) activities by ratiometric fluorescence superquenching.” J Biomol Screen 11(4): 413-422.
2) Schäfer, J., et al. (2020). “Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes.” Journal of Biological Chemistry 295(52): 18604-18613.
3) Miner, G. E., et al. (2020). “Phosphatidylinositol 3,5-bisphosphate regulates Ca2+ transport during yeast vacuolar fusion through the Ca2+ ATPase Pmc1.” Traffic 21(7): 503-517.

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