S1P Beads

Product Number: S-6110



S1P Beads are composed of agarose with 10 nanomoles of bound Sphingosine 1-Phosphate (S1P) per mL of beads, enough for several protein binding experiments. Each 1 mL order of S1P Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase.


4 °C – do not freeze<


S1P beads are designed for use in protein pull-down experiments to identify and characterize S1P binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis.

Featured in Publications

1) N. C. Hait, J. Allegood, et al. (2009) “Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate” Science 325(5945), 1254-7
2) G. M. Strub, M. Paillard, et al. (2011) “Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration” The FASEB Journal 25(2), 600-612 10.1096/fj.10-167502
3) E.-S. Park, S. Choi, et al. (2015) “Tumor Necrosis Factor (TNF) Receptor-associated Factor (TRAF)-interacting Protein (TRIP) Negatively Regulates the TRAF2 Ubiquitin-dependent Pathway by Suppressing the TRAF2-Sphingosine 1-Phosphate (S1P) Interaction” J. Biol. Chem. 290(15), 9660-9673 10.1074/jbc.M114.609685
4) Parham, K. A., et al. (2015). “Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis.” The FASEB Journal 29(9): 3638-3653.

Being bio-reactive blog: “Lipid-Ligand interaction tools: lipids are not scary intermediates anymore”


Technical Data Sheet

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com



Biochemical Reagents


Beads, Sphingolipid, Sphingosine 1-phosphate

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