PI(5)P diC8

Product Number: P-5008

$50.00$408.00

$50.00
$220.00
$408.00

Phosphatidylinositol 5-phosphate diC8 (PI(5)P diC8) is a synthetic, purified dioctanoyl PI(5)P.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases.

Alternate Names: Dioctanoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P C8, PI(5)P C8, or PI5P

Bulk discounts available, please email echelon@echelon-inc.com for information.

Publications

1) Ikonomov, O. C., D. Sbrissa, et al. (2002). “Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity.” J Biol Chem 277(11): 9206-11.
2) Hinchliffe, K. A., M. L. Giudici, et al. (2002). “Type IIalpha phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms.” Biochem J 363(Pt 3): 563-70.
3) Sbrissa, D., O. C. Ikonomov, et al. (2002). “Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells.” J Biol Chem 277(49): 47276-84.

Categories

Lipids

Filter

diC8, Phosphoinositides, PI(5)P

CAS Number

291527-92-9

Molecular Formula

C25H44Na5O19P3

Molecular Weight (g/mol)

732.53

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

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