ALC-0159

Product Number: N-2010

$131
$205
$368
$550

ALC-0159 is a PEGylated lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0159 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0315, DSPC, and cholesterol. This is a reagent grade product, for research use only. Additional information can be found here.

References
1) R. Tenchov, R. Bird, A. E. Curtze, Q. Zhou (2021) “Lipid Nanoparticles—From Liposomes to mRNA Vaccine Delivery, a Landscape of Research Diversity and Advancement” ACS Nano, DOI: 10.1021/acsnano.1c04996.
2) K.H. Moss, P. Popova, et al. (2019) “Lipid Nanoparticles for Delivery of Therapeutic RNA Oligonucleotides” Mol. Pharmaceutics 16, 2265–2277, DOI: 10.1021/acs.molpharmaceut.8b01290.
3) Y. Duan, A. Dhar, et al. (2020) “A brief review on solid lipid nanoparticles: part and parcel of contemporary drug delivery systems” RSC Adv.,10, 26777-26791.

CAS Number

1849616-42-7

Molecular Formula

(C2H4O)nC31H63NO2

Molecular Weight (g/mol)

~2330

Purity

>95%

Storage

-20 °C or below

Categories

Lipids

Filter

Ionizable/Cationic Lipids

Shipping Temp

Room Temperature

Technical Data Sheet

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