BODIPY TMR Phosphatidylinositol

Product Number: C-00M6

$322
$516

BODIPY TMR Phosphatidylinositol is a water soluble analog of Phosphatidylinositol (PI) labeled with the orange fluorophore, Bodipy®-TMR, at the sn-1 position.


Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.

Bulk discounts available, please email echelon@echelon-inc.com for information.


Categories

Lipids

Filter

Fluorescent, Phosphoinositides, PI

Excitation/Emission

542/574 nm

Molecular Formula

C33H51N5NaO17P

Molecular Weight (g/mol)

1,140.06

Purity

>95%

Storage

-20 °C or below, protect from light

Shipping Temp

Dry ice or gel ice depending on destination

Technical Data Sheet

1) Stankewicz, C. and F. H. Rininsland (2006). ” A robust screen for inhibitors and enhancers of phosphoinositide-3 kinase (PI3K) activities by ratiometric fluorescence superquenching.” J Biomol Screen 11(4): 413-422.
2) Shalhout, S. Z., et al. (2021). “YAP-dependent proliferation by a small molecule targeting annexin A2.” Nat Chem Biol 17: 767–777.
3) Schäfer, J., et al. (2020). “Neuroligin-2 dependent conformational activation of Collybistin reconstituted in supported hybrid membranes.” Journal of Biological Chemistry 295(52): 18604-18613.

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