PI4-Kinase II beta (PI4KIIb), active

Product Number: P22-10G

$245.00$353.00

$245.00
$353.00
SKU: P22-10G- Category: Tags: , , ,

Full-length recombinant human PI4KIIB was co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Enzyme obtained from SignalChem.

Molecular weight: ~84 kDa
Sequence: Full length
Species: Human
Tag: GST tag
Purity: >90 % (see TDS for lot specific information)
Specific Activity: >30 nmol/min/mg (see TDS for lot specific information)
Expression System: Sf9 insect cells using baculovirus
Genebank Number: NM_018323
Applications: PI 4-Kinase assay , western blot.
Formulation: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Storage and stability: Store product at -70ºC. Stable up to one year


Product Description:

PI4KIIB is a member of the phosphatidylinositol 4-kinase family (PI4K) that phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate which are immediate precursor of several important signaling and scaffolding molecules. PI4KIIB is primarily a cytosolic PI4K that is recruited to membranes where it stimulates phosphatidylinositol 4,5-bisphosphate syntheses. PI4KIIB uses phosphatidylinositol as their primary substrate and has no activity on phosphatidylinositol monophosphates. PI4KIIB is a restricted minor histocompatibility antigen in patients that had been successfully treated with donor lymphocyte infusions for relapsed chronic myeloid leukemia after allogeneic stem cell transplantation.


We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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Antibodies & Proteins

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Enzyme, Kinase, PI4K

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