Orexin A (human, rat, mouse)

Product Number: 471-99

$250$450

$250
$450

Molecular Weight: 3562.76
Salt Form: TFA
Purity: >95%
Sequence (3-letter): Glp-Pro-Leu-Pro-Asp-Cys-Cys-Arg-Gln-Lys-Thr-Cys-Ser-Cys-Arg-Leu-Tyr-Glu-Leu-Leu-His-Gly-Ala-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Leu-NH2 [Cys6-Cys12, Cys7-Cys14]
Sequence (1-letter): (Glp)PLPDCCRQKTCSCRLYELLHGAGNHAAGILTL-NH2

Storage: -20 °C or below

Orexin A and Orexin B are neuropeptides produced in the lateral and posterior hypothalmus. They bind the OX1 and OX2 GPCRs which are involved in food uptake. Orexin A binds to OX1 & OX2 with equal affinity while Orexin B primarily binds to OX2. In addition the Orexins have been shown to have roles in wakefulness, mood, addiction, and lipid metabolism.

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Peptides

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Metabolic / Diabetes, Neuropeptides & Hormones

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