Inositol 1,3,4-trisphosphate (Ins(1,3,4)P3)

Product Number: Q-0134

$44.00$354.00

$44.00
$200.00
$354.00
SKU: Q-0134- Category: Tags: , , ,

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,3,4-trisphosphate (Ins(1,3,4)P3) is an intermediate in the inositol phosphate pathway. Ins(1,3,4)P3 inhibits Ins(3,4,5,6)P4 1-kinase which regulates Ins(3,4,5,6)P4 levels. Ins(3,4,5,6)P4 in turn is responsible for inhibiting calcium-activated chloride channels. Ins(1,3,4)P3 is produced by dephosphorylation of Ins(1,3,4,5)P4 by a 5-phosphatase. Ins(1,3,4)P3 is a substrate for phosphatases yielding Ins(1,3)P2 and Ins(3,4)P2.


References

“Phosphatidylinositol and inositol phosphate metabolism.” J. Cell Sci. 2001, 114, 2207-8.

Keywords: D-myo-Inositol 1,3,4-trisphosphate, Ins(1,3,4)P3, or I(1,3,4)P3

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Categories

Lipids

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Inositol Phosphate

CAS Number

93133-76-7

Molecular Formula

C6H12Na3O15P3

Molecular Weight (g/mol)

486.04

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

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