Biotin Phosphatidylinositol

Biotin Phosphatidylinositol is a water soluble analog of Phosphatidylinositol (PI) labeled with biotin at the sn-1 position.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.

Storage

-20 °C

Featured in Publications

1) Bidlingmaier, S., Y. Wang, et al. (2011). “Comprehensive analysis of yeast surface displayed cDNA library selection outputs by exon microarray to identify novel protein-ligand interactions.” Mol Cell Proteomics 10(3): M110 005116.

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