1,2-Dilauroyl-sn-glycero-3-phosphate, sodium salt (DLPA) is a form of phosphatidic acid (PA), a major component of cell membranes with important biophysical, metabolic, and signaling roles. PA has been implicated in many aspects of animal cell biochemistry and physiology, including cell proliferation and differentiation, cell transformation, tumor progression and survival signaling.
Powered by Bioz| Categories | Lipids |
|---|---|
| Filter | Phosphatidic Acid |
| CAS Number | 108321-06-8 |
| Molecular Formula | C27H52NaO8P |
| Molecular Weight (g/mol) | 558.66 |
| Purity | 99% |
| Storage | 4 °C or below |
1) Lundequist, A. and J. A. Boyce (2011). “LPA5 is abundantly expressed by human mast cells and important for lysophosphatidic acid induced MIP-1beta release.” PLoS ONE 6(3): e18192.
2) Wang, Z., et al. (2019). “Phosphatidic acid generated by PLD2 promotes the plasma membrane recruitment of IQGAP1 and neointima formation.” The FASEB Journal 33(6): 6713-6725.
3) Miner, G. E., et al. (2020). “Phosphatidylinositol 3,5-bisphosphate regulates Ca2+ transport during yeast vacuolar fusion through the Ca2+ ATPase Pmc1.” Traffic 21(7): 503-517.
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