Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3,4,5)P3. This analog of PI(4,5)P2 is labeled with the red fluorophore Cyanine 5 (Cy5)
| Categories | Lipids |
|---|---|
| Filter | Fluorescent, PI(4,5)P2 |
| Molecular Formula | C75H129N6O19P3 |
| Molecular Weight (g/mol) | 1511.80 |
| Excitation/Emission | 646/662 nm |
| Purity | 95% |
| Storage | -20 °C or below, protect from light |
