cKK-E12

Product Number: N-1012

$53
$236
$415

Ionizable lipids in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. cKK-E12 has been used to deliver siRNA in mice, rats, and primates (ED50 = 0.002, 0.01, & 0.3 mg/kg respectively). It shows low toxicity and is selective for liver parenchymal cells over liver, heart, lung, and kidney endothelial cells. This product is for research use only and not for human use. Additional information can be found here.

References

Dong et al. (2014) Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates. PNAS Mar 18;111(11):3955-60


Categories

Lipids

Filter

Ionizable/Cationic Lipids

CAS Number

1432494-65-9

Molecular Formula

C60H120N4O6

Molecular Weight (g/mol)

993.64

Purity

95%

Storage

4 °C or below

Technical Data Sheet

You may also like…

  • SM-102 - Echelon Biosciences
    Lipids

    SM-102

    Product Number: N-1102

    $158$850 View products
  • 1,2-Distearoyl-sn-glycero-3-phosphocholine (DSPC) - Echelon Biosciences
    Lipids

    DSPC (18:0/18:0 PC)

    Product Number: L-1118

    $34$265 View products
  • Cholesterol - Echelon Biosciences
    Lipids

    Cholesterol

    Product Number: L-6012

    $37$172 View products
  • Dlin-MC3-DMA - Echelon Biosciences
    Lipids

    DLin-MC3-DMA

    Product Number: N-1282

    $102$625 View products
Shopping Cart
Scroll to Top

Technical Support

Bulk & Custom Orders