Ionizable lipids in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. cKK-E12 has been used to deliver siRNA in mice, rats, and primates (ED50 = 0.002, 0.01, & 0.3 mg/kg respectively). It shows low toxicity and is selective for liver parenchymal cells over liver, heart, lung, and kidney endothelial cells. This product is for research use only and not for human use.
Product Number: N-1012
cKK-E12
Ionizable lipids in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. [Read More...]