Ac-Ile-Gln-Ala-Cys-Arg-Gly-OH (Caspase Active Site Peptide)

Molecular Weight: 688.53
Salt Form: TFA
Purity: >95%
Sequence (3-letter): Ac-Ile-Gln-Ala-Cys-Arg-Gly-OH
Sequence (1-letter): Ac-IQACRG-OH
Storage: -20 °C or below

Ac-IQACRG-OH is a peptide that mimics the conserved active site of ICE-like proteases and can inhibit some cytokine-based, pro-inflammatory responses.

References

C M Troy, L Stefanis, A Prochiantz, L A Greene, and M L Shelanski. The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation. PNAS May 28, 1996 93 (11) 5635-5640