CAS Number: 191338-87-1
Molecular Weight: 506.17
Salt Form: N/A
Sequence (3-letter): Ac-Glu-Ser-Met-Asp-CHO
Sequence (1-letter): Ac-ESMD-CHO
Storage: -20 °C or below
Ac-ESMD-CHO is a peptide aldehyde that acts as a reversible inhibitor of the protease which cleaves and activates procaspase 3. The sequence corresponds to one of the cleavage sites (amino acids 25-28) of the inactive caspase-3 precursor. In a concentration range of , it It blocks the formation of the p17 subunit at 2.5-5 μM and induces accumulation of the p20 peptide.