Z-Leu-Arg-AMC (Cathepsin, Kallikrein, Falcipain II substrate, fluorogenic)

Product Number: 877-14

$158.00

$158.00
SKU: 877-14 Category: Tag:

CAS Number: 156192-32-4
Molecular Weight: 578.67
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Z-Leu-Arg-AMC
Sequence (1-letter): Z-LR-AMC
Storage: -20 °C or below

Z-Leu-Arg-AMC is a fluorogenic substrate for Cathepsins (K, L, V, S), and Kallikrein. It will also act as a substrate for Falcipains I-III but is the preferred substrate for Falcipain II. Falcipain II is a cysteine protease from Plasmodium falciparum which degrades hemoglobin and is a potential anti-malarial drug target.

Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.

 

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

Categories

Peptides

Filter

Enzyme Substrates

Shopping Cart
Scroll to Top