Z-Arg-Arg-pNA (Cathepsin B substrate)

Product Number: 866-27


SKU: 866-27 Category: Tag:

CAS Number: 201807-90-1
Molecular Weight: 584.28
Salt Form: HCl
Purity: >96%
Sequence (3-letter): Z-Arg-Arg-pNA
Sequence (1-letter): Z-RR-pNA
Storage: -20 °C or below

Z-RR-pNA is a colorimetric substrate for Cathepsin B. Cathepsin B is a lysosomal cysteine protease with a role in intracellular protein degradation. Cathepsin B crosses the blood-brain barrier and elevated levels are implicated in many neurological maladies including traumatic brain injury, epilepsy, and Alzheimer’s disease.

Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com





Enzyme Substrates

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