Z-Ala-Ala-Asp-AFC (Cathepsin S Substrate, fluorogenic)

Product Number: 874-06


SKU: 874-06 Category: Tag:

Molecular Weight: 620.54
Salt Form: N/A
Purity: >96%
Sequence (3-letter): Z-Ala-Ala-Asp-AFC
Sequence (1-letter): (Z)AAD(AFC)
Storage: -20 °C or below

Z-Ala-Ala-Asp-AFC is a fluorogenic substrate for cathepsin S, a lysosomal cysteine protease with important roles in MHC Class II antigen presentation and nociception. Cathepsin S also cleaves several extracellular matrix proteins (laminin, fibronectin elastin, osteocalcin) and glycosaminoglycans (heparin sulfate, chondroitin sulfate).

Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com





Enzyme Substrates

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