Unlabeled Shuttle PIP Carrier 3 has successfully delivered the following phosphoinositides into cells: PtdIns(3)P, PtdIns(4)P, PtdIns(5)P, and their fluorescent analogs. This carrier can also be found in these Shuttle PIP kits: P-9003, P-9004, P-9005.
To provide our customers with additional options in designing their own cell-delivery applications, Echelon offers fluorescent and non-fluorescent carriers as stand alone products outside our Shuttle PIP kits. Customers can use the most effective carrier for their system along with the individual fluorescent or non-fluorescent phosphoinositides of their choice.
Provided as 2 x 50 nmoles
Store dried product at -20 °C. Once reconstituted, store at 2-8 °C. Do not freeze thaw multiple times. Note: phosphate buffers are not recommended and may alter complex formation with phosphoinositides. We do not recommend storing carriers and PIPs together as complexes.
1) Grainger, D., C. Tavelis, et al. (2011). “Involvement of phosphatidylinositol 5-phosphate in insulin-stimulated glucose uptake in the L6 myotube model of skeletal muscle.” Pflugers Archiv European Journal of Physiology 462(5): 723-732.
2) Xu, N., X. Q. Gao, et al. (2011). “Arabidopsis AtVPS15 is essential for pollen development and germination through modulating phosphatidylinositol 3-phosphate formation.” Plant Mol Biol.
3) Pan, W., S. C. Choi, et al. (2008). “Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation.” Science 321(5894): 1350-3.