NeoBeads – PIP Purification System

Product Number: P-B999

$183.00

$183.00
SKU: P-B999- Category: Tags: , , , ,

The NeoBeads – PIP Purification System is useful in biological and chemical applications for purification of lipids. Each milligram of beads will bind at least 1 nmole phosphoinositide. The NeoBeads – PIP Purification System allows for selective purification/immobilization of phosphoinositides from biological samples. Phosphoinositides can be recovered from the beads using fresh 2 M aqueous triethylamine bicarbonate, chloroform, methanol (3:2:6; v/v). See the Technical Data Sheet for protocol and further details.

– Quick purification of Phosphoinositides from biological samples
– High Binding capacity: greater than 1 nanomole phosphoinositide per mg bead
– Reproducable batches: low lot-to-lot variability
– Cited in multiple scientific papers over 20+ years describing uses, techniques and protocols.
– First commercially available solid-supported neomycin

References

1) A. Grey, H. Olsson, I.H. Batty, L. Priganica, C.P. Downes: Nonradioactive methods for the assay of phosphoinositide 3-kinases and phosphoinositide phosphates and selective detection of signaling lipids in cell and tissue extracts. Analytical Biochemistry 313 234-245 (2003).
2)Sbrissa, D., Ikonomov, O. C., Deeb, R., and Shisheva, A., Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells, J Biol Chem, 277, 47276 (2002).
3) Sierra Potchanant, E. A., et al. (2016). “INPP5E preserves genomic stability through regulation of mitosis.” Mol Cell Biol 37: e00500-00516.

Keywords: phosphoinositide, purification, PIP, beads, resin


Documents

Technical Data Sheet

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

Categories

Biochemical Reagents

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Beads, Phosphoinositides

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