TMR Labeled Carrier 1 (Neomycin B Sulfate)

Neomycin-TMR is labeled with a red dye (tetramethylrhodamine) and has successfully delivered the following phosphoinositides into cells: PtdIns(4,5)P₂, PtdIns(3,4)P₂, PtdIns(3,5)P₂, PtdIns(3,4,5)P₃, and their fluorescent analogs.

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To provide our customers with additional options in designing their own cell-delivery applications, Echelon offers fluorescent and non-fluorescent carriers as stand alone products outside our Shuttle PIP kits. Customers can use the most effective carrier for their system along with the individual fluorescent or non-fluorescent phosphoinositides of their choice.

Provided as 2×10 nmoles.

Storage

Protect from moisture and light and store at -20 °C until reconstituted. Reconstitute with water or other aqueous solutions and store at 4 °C in the dark after reconstituting for up to 3 months. Multiple freeze thawing is not recommended. Note: phosphate buffers are not recommended and may alter complex formation with phosphoinositides. We do not recommend storing carriers and PIPs together as complexes.

Featured in Reference

1) Hao, M. and J. S. Bogan (2009). “Cholesterol regulates glucose-stimulated insulin secretion through phosphatidylinositol 4,5-bisphosphate.” J Biol Chem 284(43): 29489-98.

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