Sphingo Beads

Product Number: S-6100

$133.00$691.00

$133.00
$691.00

Sphingo Beads are composed of agarose with 10 nanomoles of bound Sphingosine per mL of beads, enough for several protein binding experiments. Each 1 mL order includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase.


Storage

4 °C – do not freeze

Applications

Sphingo Beads are designed for use in protein pull-down experiments to identify and characterize sphingosine binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis.

Featured in Publications

1) Alvarez, S. E., et al. (2010). “Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.” Nature 465(7301): 1084.
2) Takasugi, N., et al. (2011). “BACE1 activity is modulated by cell-associated sphingosine-1-phosphate.” J Neurosci 31(18): 6850-6857
3) Parham, K. A., et al. (2015). “Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-γ that regulates neoangiogenesis.” The FASEB Journal 29(9): 3638-3653.
4) Nair, S., et al. (2018). “Antigen-mediated regulation in monoclonal gammopathies and myeloma.” JCI insight 3(8) e98259.

Being bio-reactive blog: “Lipid-Ligand interaction tools: lipids are not scary intermediates anymore”


Documents

Technical Data Sheet

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

Categories

Biochemical Reagents

Filter

Beads, Sphingolipid, Sphingosine

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