Molecular Weight: 1053.67
Salt Form: TFA
Sequence (3-letter): Myristoyl-Leu-Ser-Glu-Thr-Lys-Pro-Ala-Val-OH
Sequence (1-letter): (Myristoyl)LSETKPAV-OH
Storage: -20 °C or below
Protein kinase C epsilon, PKC(e), is involved in the regulation of diverse cellular functions including neurotransmitter release in the brain. Translocation of PKC(e) is a marker of activity and can be blocked with isozyme specific peptides. (Myristoyl)LSETKPAV-OH is a scrambled peptide that serves as a negative control for inhibition of PKC(e) translocation.
Obis et al. (2015) The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release. Molecular Brain (8)