PKC Isoenzyme Inhibitor (myristoylated)

Molecular Weight: 1054.34
Salt Form: TFA
Purity: >95%
Sequence (3-letter): N-Myr-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
Sequence (1-letter): (Myristoyl)EAVSLKPT-OH
Storage: -20 °C or below

Protein kinase C epsilon, PKC(e), is involved in the regulation of diverse cellular functions including neurotransmitter release in the brain. Translocation of PKC(e) is a marker of activity and can be blocked with isozyme specific peptides. This peptide is the myristoylated version of an octapeptide PKC(e) inhibitor (Cat# 880-15). Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH is a selective inhibitor of the translocation of PKC(e). It can be used to resolve the functions of PKC(e) from those of other PKC isozymes.