PKC Isoenzyme Inhibitor (myristoylated)

Product Number: 880-17

$129.00

$129.00
SKU: 880-17 Category:

Molecular Weight: 880.17
Salt Form: TFA
Purity: >95%
Sequence (3-letter): N-Myr-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
Sequence (1-letter): (Myristoyl)EAVSLKPT-OH
Storage: -20 °C or below

Protein kinase C epsilon, PKC(e), is involved in the regulation of diverse cellular functions including neurotransmitter release in the brain. Translocation of PKC(e) is a marker of activity and can be blocked with isozyme specific peptides. This peptide is the myristoylated version of an octapeptide PKC(e) inhibitor (Cat# 880-15). Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH is a selective inhibitor of the translocation of PKC(e). It can be used to resolve the functions of PKC(e) from those of other PKC isozymes.

References

Obis et al. (2015) The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location, regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release. Molecular Brain (8)

 

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

Categories

Peptides

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