Phosphatidylinositol 5-phosphate diC4 (PI(5)P diC4) is a synthetic, purified dibutanoyl PI(5)P.
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases.
Alternate Names: D-myo-Phosphatidylinositol 5-phosphate, Dibutanoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P C4, PI(5)P C4, or PI5P
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4) Boal, F. d. r., A. Puhar, et al. (2016). “PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment.” Cell Reports., doi:10.1016/j.celrep.2015.12.079