PolyPIPosomes are polymerized liposome-like nanoparticles (~200 nm) which show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents or coated surfaces.
PolyPIPosomes have demonstrated utility in a number of assay formats:
- Protein pull-down
- Surface Plasmon Resonance
- Liposome overlay assay
PI(3,4)P2 PolyPIPosomes are provided as a 1mM total lipid solution containing 5% PI(3,4)P2. Each order of 250 μL or 1 mL of PolyPIPosomes includes 100 μL of Control PolyPIPosomes.