PI(3,4,5)P3 diC16 (ammonium salt)

Product Number: P-3916A

$39.00$311.00

$39.00
$175.00
$311.00

PI(3,4,5)P3 diC16 (Phosphatidylinositol 3,4,5-trisphosphate diC16) ammonium salt is a synthetic, purified dipalmitoyl PI(3,4,5)P3.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2.

Featured in Publications

AJP – Renal Physiology, Apr 2006

AJP – Lung Cellular and Molecular Physiol, Mar 2006

Product Keywords: Dipalmitoyl Phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4,5)P3 C16, PI(3,4,5)P3 C16, or PIP3

Bulk discounts available, please email echelon@echelon-inc.com for information.

Categories

Lipids

Filter

diC16, Phosphoinositides, PI(3,4,5)P3

CAS Number

165689-82-7

Molecular Formula

C41H94N4O22P4

Molecular Weight (g/mol)

1,118.5

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

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