PI(3,4,5)P3 18:0/20:4

Product Number: P-3924

$145.00$1,085.00

$145.00
$639.00
$1,085.00

PI(3,4,5)P3 (Phosphatidylinositol 3,4,5-trisphosphate) 18:0/20:4 is a synthetic, purified PI(3,4,5)P3 with stearoyl and arachidonoyl acyl groups.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2.


Product Keywords: 1-Stearoyl-2-arachidonoyl-phosphatidylinositol 3,4,5-trisphosphate, PtdIns(3,4,5)P3 (18:0/20:4), PI(3,4,5)P3 (18:0/20:4), or PIP3

Bulk discounts available, please email echelon@echelon-inc.com for information.

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Phosphoinositides, PI(3,4,5)P3

CAS Number

799268-60-3

Molecular Formula

C47H82Na4O22P4

Molecular Weight (g/mol)

1,214.99

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

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