PI3-K alpha Inhibitor 2

Product Number: B-0304


3-(4-Morpholinothieno[3,2-d]pyrimidin-2-yl)phenol is a selective inhibitor for the α-isoform of PI 3-Kinase (IC50: PI 3-Kα = 2 nM, PI 3-Kβ = 16 nM, PI3-Kγ = 660 nM, PI3KC2β = 220 nM)). It showed >1000-fold selectivity vs. protein kinases such as PKA, KDR, PKCa, and E/CDK2 (IC50 = 91, 3.4, 466, 288 μM). It inhibited proliferation of A375 melanoma cells at 580 nM. Also known as PI3-K Inhibitor 2, PIK2.


1) M. Hayakawa, et al. “Synthesis and biological evaluation of 4-morpholino-2-phenyl quinazolines and related derivatives as novel PI3 kinase p110a inhibitors” Bioorg. Med. Chem. 2006, 14, 6847-6858.


Biochemical Reagents


Inhibitor, PI3K

CAS Number


Molecular Formula


Molecular Weight (g/mol)





4 °C or below

Shipping Temp

Ambient Temperature

Technical Data Sheet

You may also like…

  • Wortmannin (KY 12420) - Echelon Biosciences
    Biochemical Reagents


    Product Number: B-0222

    $41$111 View products
  • PI-103 (PI3-K alpha Inhibitor 1) - Echelon Biosciences
    Biochemical Reagents

    PI-103 (PI3-K alpha Inhibitor 1)

    Product Number: B-0303

    $33$136 View products
  • PI3-Kinase Activity ELISA: Pico - Echelon Biosciences
    Kits & Assays

    PI3-Kinase Activity ELISA: Pico

    Product Number: K-1000S

    $380 View products
  • LY294002 (PI3-K Inhibitor) - Echelon Biosciences
    Biochemical Reagents

    LY294002 (PI3-K Inhibitor)

    Product Number: B-0294

    $45$204 View products
Shopping Cart
Scroll to Top

Technical Support

Bulk & Custom Orders