CAS Number: 133407-86-0
Molecular Weight: 461.29
Salt Form: N/A
Sequence (3-letter): Z-Leu-Leu-Nva-CHO
Sequence (1-letter): Z-LL(Nva)-CHO
Storage: -20 °C or below
MG-115 (Z-Leu-Leu-Nva-CHO) is a potent, cell permeable inhibitor of the 20S proteosome. It forms a reversible hemiacetal adduct and can also inhibit cathepsins and calpains. It reduces degradation of ubiquitinated proteins and blocks proteolytic conversion of protein precursors. MG-115 is known to induce the heat shock response and apoptosis.