Juvenile Hormone III (racemic)

Juvenile Hormone III (JH III) is a sesquiterpanoid found in insects which regulates important physiological processes such as reproduction and metamorphosis. JH III is biosynthesized via the mevalonate pathway and is metabolized by JH esterase and JH epoxide hydrolase terminating the activity of the hormone. JH III has also been found in certain plants such as Cyperus iria and C. Aromaticus potentially acting as a protectant against insect herbivory.

Storage

-20 °C or below

References

1) C. Helvig, et al. “CYP15A1, the cytochrome P450 that catalyzes epoxidation of methyl farnesoate to juvenile hormone III in cockroach corpora allate” Proc. Nat. Sci. Acad. 2004, 101(12), 4024–4029
2) J.A. Tillman, S.J. Seybold, R.A Jurenka, R.A., et al. “Insect pheromones – an overview of biosynthesis and endocrine regulation.” Insect Biochemistry and Molecular Biology, 1999, 29(6), 481-514.
3) Y.C. Toong, D.A. Schooley, & F.C.Baker. “Isolation of Insect Juvenile Hormone III from a plant” Nature, 1988, 333, 170-171.

Alternate Names: trans-trans-10,11-Epoxyfarnesenic Acid methyl ester