Inositol 1,4,5-trisphosphate (Ins(1,4,5)P3)

Product Number: Q-0145

$33.00$114.00

$33.00
$63.00
$114.00
SKU: Q-0145- Category: Tags: , , ,

Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), aka IP3, is a second messenger produced by phospholipase C catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2). IP3 binds to the IP3-receptor on the endoplasmic reticulum causing calcium to be released through the opening of a tetrameric ion channel. IP3 is rapidly metabolized by a specific series of inositol phosphatases and kinases.


References

“Phosphatidylinositol and inositol phosphate metabolism.” J. Cell Sci. 2001, 114, 2207-8.

Keywords: D-myo-Inositol 1,4,5-trisphosphate, Ins(1,4,5)P3, I(1,4,5)P3, or IP3

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Categories

Lipids

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Inositol Phosphate

CAS Number

108340-81-4

Molecular Formula

C6H12Na3O15P3

Molecular Weight (g/mol)

486.04

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

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