Molecular Weight: 1096.34
Salt Form: TFA
Sequence (3-letter): Val-Tyr-Leu-Lys-Thr-Asn-Val-Phe-Leu-OH
Sequence (1-letter): VYLKTNVFL-OH
Storage: -20 °C or below
Islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) is an autoantigen in mouse models of type 1 diabetes and is a potential autoantigen in humans. IGRP (206-214) represents a fragment of the catalytic subunit of IGRP that primes and is recognized by islet-associated CD8+ T cells in type 1 diabetes.