Gamma Secretase Inhibitor

Product Number: 649-27

$204.00

$204.00

CAS Number: 133407-83-7
Molecular Weight: 475.3
Salt Form: N/A
Purity: >95%
Sequence (3-letter): Z-Leu-Leu-Nle-CHO
Sequence (1-letter): Z-LL(Nle)-CHO
Storage: -20 °C or below
Solubility: DMSO > 1 mg/mL

Gamma Secretase Inhibitor, sequence Z-Leu-Leu-Nle-CHO (Z-Leu-Leu-Nle-al), is a leupeptin analog which inhibits gamma secretase. Gamma secretase is a membrane associated protein complex consisting of presenilin, nicastrin, Aph-1, and Pen-2. It catalyzes the cleavage of Notch and Beta Amyloid proteins and is implicated in Alzheimer’s disease.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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Peptides

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Central Nervous System, Inhibitor

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