DOTMA forms stable cationic liposomes in solution and can be used in the cell transfection of DNA, RNA, oligonucleotides, anionic proteins, and small peptides. DOTMA increased by at least 1000-fold the activity of an antisense oligonucleotide (ISIS 1570) in human umbilical vein endothelial cells.
| Categories | Lipids |
|---|---|
| Filter | Ionizable/Cationic Lipids |
| CAS Number | 104872-42-6 |
| Molecular Formula | C42H84NO2Cl |
| Molecular Weight (g/mol) | 670.57 |
| Purity | >95% |
| Storage | -20 °C or below |
| Shipping Temp | Room Temperature |
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