d5-POPEth

Product Number: L-6051

$100.00$166.00

$100.00
$166.00
SKU: L-6051- Category: Tags: , ,

Phosphatidylethanol (PEth) is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phosphlipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes, and is one of the longest-lived circulating EtOH metabolite yet identified. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol-d5 (d5-POPEth) has a fully deuterated ethanol headgroup and can be used as a mass spectrometry standard.

Categories

Lipids

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Deuterated Lipids, Phosphatidylethanol

CAS Number

1612215-96-9 (161240-92-7 ammonium salt)

Molecular Formula

C39H73D5NO8P

Molecular Weight (g/mol)

725.04

Purity

95%

Storage

-20 °C or below

Technical Data Sheet

1) Javors, M. A., et al. (2016). “Characterization of the Pharmacokinetics of Phosphatidylethanol 16:0/18:1 and 16:0/18:2 in Human Whole Blood After Alcohol Consumption in a Clinical Laboratory Study.” Alcohol Clin Exp Res 40(6): 1228-1234.
2) Thompson, P. M., et al. (2016). “Phosphatidylethanol in Postmortem Brain and Serum Ethanol at Time of Death.” Alcohol Clin Exp Res 40(12): 2557-2562.
3) McDonell, M. G., et al. (2017). “Pilot investigation of a phosphatidylethanol-based contingency management intervention targeting alcohol use.” Psychol Addict Behav 31(5): 608-613.
4) van der Nagel, B. C. H., et al. (2018). “Quantification of phosphatidylethanols in whole blood as a proxy for chronic alcohol consumption, using ultra performance convergence chromatography tandem mass spectrometry.” Ther Drug Monit 40(2): 268-275.
5) Aboutara, N., et al. (2021). “Analysis of six different homologues of phosphatidylethanol from dried blood spots using liquid chromatography-tandem mass spectrometry.” Drug Test Anal 13(1): 140-147.
6) Hofmann, V., et al. (2022). “Development and validation of an analytical method for the simultaneous determination of the alcohol biomarkers ethyl glucuronide, ethyl sulfate, N-acetyltaurine, and 16:0/18:1-phosphatidylethanol in human blood.” Drug Testing and Analysis 14(1): 92-100.

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