Phosphatidylethanol (PEth) is formed primarily by transphosphatidylation of phosphatidylcholine (PC) by phosphlipase D. Most PEth (about 75%) is incorporated into erythrocyte membranes, and is one of the longest-lived circulating EtOH metabolite yet identified. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol-d5 (d5-POPEth) has a fully deuterated ethanol headgroup and can be used as a mass spectrometry standard.
| Categories | Lipids |
|---|---|
| Filter | Deuterated Lipids, Phosphatidylethanol |
| CAS Number | 1612215-96-9 (161240-92-7 ammonium salt) |
| Molecular Formula | C39H73D5NO8P |
| Molecular Weight (g/mol) | 725.04 |
| Purity | 95% |
| Storage | -20 °C or below |
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4) van der Nagel, B. C. H., et al. (2018). “Quantification of phosphatidylethanols in whole blood as a proxy for chronic alcohol consumption, using ultra performance convergence chromatography tandem mass spectrometry.” Ther Drug Monit 40(2): 268-275.
5) Aboutara, N., et al. (2021). “Analysis of six different homologues of phosphatidylethanol from dried blood spots using liquid chromatography-tandem mass spectrometry.” Drug Test Anal 13(1): 140-147.
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