D-Val-Leu-Arg-AFC (Kallikrein substrate, fluorogenic)

Product Number: 871-84


SKU: 871-84 Category: Tag:

Molecular Weight: 597.29
Salt Form: HCl
Purity: >96%
Sequence (3-letter): D-Val-Leu-Arg-AFC
Sequence (1-letter): vLR-AFC
Storage: -20 °C or below

D-Val-Leu-Arg-AFC is a fluorogenic substrate for the serine protease glandular tissue kallikrein. Kallikrein is responsible for the regulation of blood pressure and activation of inflammation by releasing kinins (bradykinin and kallidin) from kinogens.

Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com





Enzyme Substrates

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