Cell Permeable Caspase 3 Inhibitor

Product Number: 864-29

$91.00$175.00

$91.00
$175.00
SKU: 864-29 Category: Tags: ,

Molecular Weight: 1999.1
Salt Form: N/A
Purity: >90%
Sequence (3-letter): Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO
Sequence (1-letter): Ac-AAVALLPAVLLALLAPDEVD-CHO
Storage: -20 °C or below

A cell-permeable inhibitor with the potent, caspase 3 selective sequence DEVD-CHO at the C-terminus (Ki < 1 nM). It will also inhibit PARP cleavage in cultured human osteosarcoma cell extracts (IC50 = 200 pM). Cell permeability is conferred by the 16-residue N-terminal sequence  corresponding to the hydrophobic region (h-region) of the signal peptide of Kaposi fibroblast growth factor (K-FGF) .

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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