Cardiolipin Beads are composed of agarose with 10 nanomoles of bound cardiolipin per 1ml of beads, enough for several protein binding experiments. Each 1 mL order includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase.
Storage: 4 °C – do not freeze
Applications: Cardiolipin Beads are designed for use in protein pull-down experiments to identify and characterize lipid binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis.
Publications
Powered by BiozBeing bio-reactive blog: “Lipid-Ligand interaction tools: lipids are not scary intermediates anymore”
1) Singh, S. B., W. Ornatowski, et al. (2010). “Human IRGM regulates autophagy and cell-autonomous immunity functions through mitochondria.” Nat Cell Biol 12(12): 1154-1165.
2) Stein, C. S., et al. (2018). “Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency.” Cell Reports 23(13): 3710-3720.e3718.
3) Cory J. Anderson, et al. (2018). “Prohibitin is a positive modulator of mitochondrial function in PC12 cells under oxidative stress.” Journal of Neurochemistry 146: 235-250.
