Caerulein (ceruletide)

Product Number: 471-65

$188.00$730.00

$188.00
$730.00
SKU: 471-65 Category: Tags: , , , ,

CAS Number: 17650-98-5
Molecular Weight: 1352.43
Salt Form: N/A
Purity: >95%
Sequence (3-letter): Glp-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2 (Glp = Pyroglutamic acid)
Sequence (1-letter): (Glp)QD(Tyr(SO3H))TGWMDF-NH2
Storage: -20 °C or below
Solubility: water, >1 mg/mL

Caerulein is a sulfated peptide that is used in the study of NF-κB-mediated signaling. When administered via i.v., it can produce analgesia. It has also been shown to induce pancreatitis in animals at high doses and prevent pain associated with gall-bladder contraction and intermittent claudication.

References

1. Baber, N.S., Dourish, C.T. and Hill, D.R. (1989) “The role of CCK, caerulein, and CCK antagonists in nociception” Pain 9: 307-328.
2.Watanabe, O. et al (1984) “Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis” Am. J. Physiol. 246(4 Pt 1): G457-67.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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Peptides

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Gastrointestinal

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