C12-200 is an ionizable lipid used in lipid nanoparticles (LNPs). LNP compositions have proven effective as transport vehicles into cells and/or intracellular compartments for biologically active substances such as small molecule drugs, proteins and nucleic acids.
| Categories | Lipids |
|---|---|
| Filter | Ionizable/Cationic Lipids |
| CAS Number | 1220890-25-4 |
| Molecular Formula | C70H145N5O5 |
| Molecular Weight (g/mol) | 1136.96 |
| Purity | >90% |
| Storage | -20 °C or below |
1) Kevin T. Love et al; Lipid-like materials for low-dose in vivo gene silencing, PNAS, 2010, 107(5): 1864-1869.
2) Whitehead, K. A. et al. Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nat. Commun. 2014, 5:4277, doi: 10.1038/ncomms5277.
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