Bradykinin B2 Antagonist (HOE 140)

Product Number: 191-85

$91
$316

CAS Number: 138614-30-9
Molecular Weight: 1303.66
Salt Form: TFA
Purity: >96%
Sequence (3-letter): D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH
Sequence (1-letter): rRP(Hyp)G(Thi)S(D-Tic)(Oic)R-OH
Storage: -20 °C or below

Bradykinin B2 Antagonist (HOE 140, Icatibant) has been shown to inhibit microvascualar leakage in a liver cirrhosis model. It also acts as an Aminopeptidase N inhibitor (Ki = 9.1 μM). Bradykinin is a potent vasodilator peptide that exerts its action through stimulation of specific endothelial receptors. It has been linked with the pathophysiological process that accompanies tissue damage and inflammation.

Categories

Peptides

Filter

Neuropeptides & Hormones

Shopping Cart
Scroll to Top

Technical Support

Bulk & Custom Orders