CAS Number: 31362-50-2
Molecular Weight: 1618.82
Salt Form: TFA
Sequence (3-letter): Glp-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2
Sequence (1-letter): (Glp)QRLGNQWAVGHLM-NH2
Storage: -20 °C or below
Solubility: Soluble in water (1 mg/mL)
Bombesin is a neuropeptide, originally isolated from amphibian skin (cat # 177-25 is fully synthetic), with biological activity in the gastrointestinal tract in addition to the central nervous system. Biological effects include inhibiting gastric emptying, modulating secretion of gastric acid, and stimulating secretion of pancreatic enzymes. In rats, it has been shown to suppress feeding.
Glp = Pyroglutamic acid
1.Cuttitta, F. et al. (1985) “Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer” Nature 316: 823-826.
2. Rowe, E.A. et al. (1979) “Bombesin suppresses feeding in rats” Nature 282 (8): 208-210.