Endothelin 3, cyclic (human, mouse, rabbit, rat)

Product Number: 335-10

$222.00$358.00

$222.00
$358.00

CAS Number: 117399-93-6
Molecular Weight: 2645.16
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Cys1-Cys15, Cys3-Cys11)
Sequence (1-letter): CTCFTYKDKECVYYCHLDIIW-OH
Storage: -20 °C or below
Solubility: water >1 mg/mL

Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. Endothelin-3 is an endogenous neuropeptide and potent vasoconstrictor. Endothelin-3 has been reported to attenuate thrombin-evoked aggregation of human platelets, acts as a potent stimulator of interleukin-6 production by endothelial cell lines, activates phospholipase C in fibroblasts expressing ETA receptors and induces the production of VEGF.

References

1. Baynash, A.G. (1994) “Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons” Cell 79 (7): 1277–1285.
2. Matsumoto, H. et al. (1989) “Abundance of endothelin-3 in rat intestine, pituitary gland and brain” 164 (1): 74-80.
3. Sakamoto, A. et al. (1991) “Cloning and functional expression of human cDNA for the ETB endothelin receptor” Biochem. Biophys. Res. Commun. 178 (2): 656–663

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

Categories

Peptides

Filter

Cardiovascular, Neuropeptides & Hormones

Shopping Cart
Scroll to Top